User blog comment:Bacon mincher/please help!/@comment-4647112-20120111135358

If you want to beat the Destroyer the Magical Harp with Magic Power Potions would be a good choice. For the Twins and Skeletron use ranged Wapons like the Megashark with Crystalbullets and Iron Skin -, Swiffnes - and Gravitation Potions.

Hope i helped you a bit :D