Ankh Shield

The Ankh Shield is created by crafting an Obsidian Shield and an Ankh Charm at a Tinkerer's Workshop. This provides immunity to knockback and fire blocks, as well as the Weak, Broken Armor, Poisoned, Bleeding, Slow, Confused, Silenced, Cursed, Darkness and The Tongue debuffs.

The Ankh Shield currently entails the most complex crafting tree in Terraria. See Guide:Ankh Shield for a layout.

Trivia

 * Of the accessories, the Ankh Shield and the Celestial Stone gives the second most base defense, being bested only by the Paladin's Shield which has 6 base defense (However, you will take more damage if playing multiplayer).
 * The Ankh Shield is the combination of 11 different individual accessories: Bezoar, Vitamins, Cobalt Shield, Obsidian Skull, Nazar, Blindfold, Trifold Map, Fast Clock, Megaphone, Armor Polish, and Adhesive Bandage. This makes it the most compact accessory in the game.
 * The Ankh Shield can remove all but two of the debuffs applied to someone wearing a developer item such as Red's Wings.
 * You will need a world with several hardmode enemies, materials, and crafting stations to craft the Ankh Shield. Here is a crafting guide.
 * There are ten debuffs that can occur that this cannot block; Blackout, Ichor, Cursed Inferno, Chilled, Frozen, Frostburn, Potion Sickness, Venom, Tipsy, and On Fire!.