Board Thread:New on Terraria Wiki/@comment-74.101.126.88-20121218114129/@comment-6537153-20130705211451

Don't kill The Eye of Cthulu. It's a huge waste of time. Go for The Eater of Worlds right away. Build a small arena, then, cave untill you get 50 silver. Make a home, get the Merchant spawned. Spend all money on Shurikens and if you've got a Demolitionist (gotten by collecting bombs) buy some gernade as they don't make terrain explode. Kill Eater of Worlds, get enough stuff, i.e. armor. Then, smash Shadow Orbs and get a Musket. Use it against Skeletron, if having trouble, find a boulder trap, destroy boulder and 2 active stone blocks and put one in the wiring and one right next to the one previously placed, place a chest and place an item in it and dupe it and then get a Minishark.

There's a guide up to skeletron.