Board Thread:Game Help/@comment-30754266-20170922112043/@comment-4661596-20170922175241

You can't really say which is easiest or hardest, because it will depend heavily on your gear and weapon choices. From my various experiences, I do find Skeletron Prime to be overall the easiest, because he isn't too hard to dodge, even if you don't prepare with an arena. With enough defense to withstand some occasional hits from the arms, its a pretty straight forward battle. The Destroyer can be annoying if there are too many probes firing at you, and his head packs a really mean punch in expert mode. The Twins are hard in the sense that they are fast and hard to avoid damage from. Now saying this, The Destroyer can be very easy if you take the time to get a Daedalus Stormbow, and some Holy Arrows. Skeletron Prime is also pretty easily defeated this way. I find the Twins are harder to target with this weapon. Another simpler approach to the Destroyer is to make a large box to encase yourself in, and fight it melee-style when it passes through the box. This will help keep control of too many probes hitting you from everywhere.