User blog comment:CaptainLocoMoco/Please help me figure out how to kill the destroyer!/@comment-184.166.120.114-20111211054807

If you get a Demon Scythe with a good reforge(Mine has Hurtful) it's cake with good armor. Get Ironskin, Regeneration, Clarvoyance(spelling),Thorns, and you should be good to go.