User blog comment:Mathmagician/Wall of Flesh Solo Guide/@comment-109.186.46.198-20111219124326/@comment-4674838-20111220035208

Suppose that you and I are using exactly the same gear, except that I get +20 defense from my accessories and you get +20% damage from yours. Let's say that we're both using Crystal Storm, and that we can both shoot The Twins 50 times for each time The Twins hit us once. Let's say that you do 60 damage with your Crystal Storm per hit, meaning that I do 50 damage per hit. We both have the same critical hit %.

After we each get hit 10 times, I have 100 more life than you (my defense is 20 higher than yours, so for each of the 10 hits I take 10 less damage than you). On the other hand, you've managed to do 500 x (60 - 50) = 5000 more damage to the Twins than I have.

I have 100 more life than you, which is 25% of the player's 400 max HP. But you've done 5000 more damage than I have, which is only about 10.4% of The Twin's overall 48000 HP. So my choice of gear under this typical scenario is superior to yours.

In order for your choice of gear to be better than mine, you will need to VASTLY improve your number of shots that hit the Twins for each time the Twins hit you, or otherwise you need some super powerful healing methods. In other words, either you need to dodge and aim like a pro gamer, or you need to have a dozen heart statues lying around. Can you see now why just having more defense is a smart choice?