Board Thread:General Discussion/@comment-30975509-20170421070427/@comment-4661596-20170421153257

This question doesn't really have one answer, it just depends on what weapons you want to use really. Seeing as how you know what each armor does, you just pick one that goes well with the weapon you like to use, and the accessories you have. If a certain boss is defeated with a certain set up more easily than others, then guess what....you use that. Maybe you are asking which one to stick with for overall playthrough? Even then its just what you feel like trying. I myself always go for the best defense set up if I am soloing. I can do damage good enough with damage boosts, and I can withstand damage to myself without dying over and over.