Guide:Duke Fishron strategies

Duke Fishron is a flying fish/pigron boss with very high movement speed and high damage, making it the most difficult boss in the game so far.

It is advised to use life-draining weapons on him and high movement speed.

Terrain preparation

 * Make an arena (like one for Dungeon Guardian). Asphalt blocks are highly recommended. But don't make the arena too high or long or Duke Fishron may disappear.
 * As he flies it is also useful to be able to fly to, the hover-board is extremely useful for dodging attacks. Also equip Lightning Boots to move even faster.
 * Teleporters may help you much if you have enough resources.

Fishron will follow you on land as well, so make 300-400 pieces long arena, then when you fight him, just run away with the lightning boots or similar and shoot back at him. Then at the end of the arena or if he catches you, you fly up with wings, hoverboard etc. and avoid him and start running back at the other end of the arena. When you use this correctly, sharknados will be left behind and they won't hit you at all and fishron only hits you in the end of the arena once if you are not able to avoid him.

Armor

 * For life-draining is advisable equip the Spectre armor with the Spectre Hood.
 * For dodging skills is advisable equip the Titanium armor for Shadow dodge buff and Master Ninja Gear as optional.
 * For high defense and melee Beetle armor with Vampire Knives are advised.

Weapons

 * For magic it's recommended use Homing weapons like Bat Scepter or Spectre Staff, or rapid weapons like Razorpine or Leaf Blower. They must be equipped with many increasing damage bonuses for fast healing. However, lots of Mana potions is required.
 * For melee the best is Vampire Knives for stealing life combined with high damage and defense or saving mana.
 * A Golden Shower or Flask of Ichor is useful to slightly low its defense.

Accessories

 * A must is Hoverboard and Lightning Boots or better as primary choice. Also a Shield to prevent knockback from tornados.
 * If you choose magic, equip a Mana Flower and magic or damage increasing items. All equipped items should have damage or Arcane modifiers.
 * If you choose melee, equip increasing melee damage items like Celestial Stone. All equipped items should have damage or defensive modifiers.

Potions
Like any other Hardmode boss, equip the next potions:
 * Greater Healing Potions though is not much necessary as you equip life-draining weapons
 * Regeneration Potion and Ironskin Potion (specially if you use Spectre armor) to survive. Two of each will last enough.
 * Pumpkin Pies will likely last the entire fight, and it's easy to craft.
 * Swiftness Potion helps you a lot to evade the Pigron and it's attacks.
 * If you have access to a Crystal Ball, activate it just before the fight. It will likely last the entire fight.

The battle
Basically is just shooting him while running around and jumping and go back to avoid getting hit. Duke Fishron has 50000 health making it difficult to beat. When it uses detonating bubbles is not much problem if you run and dodge its attacks. For tornados it may be a painful obstacle but you can recover your health fast if given enough time, Sharknados are not problem as they are more likely to die very fast. If you use the Titanium armor the Shadow dodge buff will help you with tornados to avoid getting much damage. If you use Beetle armor with Vampire knives with very high damage bonuses it can be less difficult to beat him and you are more likely to survive.

Tips
For AFK purposes (not tested yet):
 * Using Bat Specter and Cross Necklace with all damage and defense increase possible you gain more health than damage.
 * Also affects with the vampire knives but you have to aim well.