Potion Sickness

Potion Sickness is a debuff inflicted on a player whenever they use a healing item. It prevents the player from consuming any more healing items until the debuff runs out. Its duration can be reduced by 25% by equipping the Philosopher's Stone or the Charm of Myths. Equipping both will not cause the effect to stack.

For nearly all healing items, the Potion Sickness debuff lasts 60 seconds, after which time another can be consumed.

Trivia

 * The debuff uses the Lesser Healing Potion's pre-1.3.0.1 sprite.
 * It is usually the first debuff players encounter.
 * Potion Sickness is a play on .
 * The Restoration Potion and the  Mushroom are the only two consumables which inflict the Potion Sickness debuff for less than 60 seconds.
 * On the, when the buff menu is open, the potion sickness duration will continue to decrease despite the game being paused.