The Axe

The Axe is a Hamaxe (Abilities of an Axe and a Hammer) dropped rarely by the Jungle hardmode Boss Plantera. With 175% axe power and 100% hammer power, it is the most powerful axe and hammer in the game (in terms of mining power). Surprisingly it is also one of the strongest melee weapons in the game,only losing by 8 base damage from the Terra Blade, the strongest sword in the game.

Referencing its appearance, it makes electric guitar sounds every few hits.

This is most likely a reference to the metal band Pantera's lead guitarist "Dimebag" Darrell, who used to use a red Flying V guitar.