Ice Queen

The Ice Queen is the final boss during the Frost Moon. She is the equivalent to the Pumpking from the Pumpkin Moon, being the Frost Moon's most powerful monster, coming in at the latest waves of the event, and being the only boss from the event with the ability to fly. As of the 1.2.2 update, she is the strongest enemy type in Terraria.

Her behavior is characterized by astonishingly fast movement and evasive maneuvers while making constant attacks against the player. There are two ways to counter this - either use wings and possibly movement enhancing accessories to chase her, or a Cross Necklace/Star Veil combined with healing (Spectre armor) to mitigate her damage. In both cases a powerful ranged/magic weapon with high fire velocity is recommended. If a bullet-firing weapon is used, it may be a good idea to equip the Rifle Scope (or, even better, the Sniper Scope) as she will be off-screen for a majority of the battle, and is sometimes difficult to keep track of during the fight.

Trivia

 * Whereas the final boss of the Frost Moon is the Ice Queen, the final boss of the Pumpkin Moon is the Pump king.
 * A possible Adventure Time reference