User blog comment:CaptainLocoMoco/Please help me figure out how to kill the destroyer!/@comment-4674838-20111213193235/@comment-4658608-20111213201330

If using Cross Necklace and Adamantite Armor (or no necklace and cobalt/mythril) you can also bury yourself in sand, taking very little damage constantly (less than the Destroyer will do on his own), which may obviate the need to collect hearts from probes at all, while swinging with a sword (Phasesabre is probably your best bet pre-destroyer. Legendary upgraded.)  You can also get the Warrior's Emblem from WOF.

The average player will find this boss to be the easiest of the three. And the Megashark you get from killing it will make short work of the other two hardmode bosses, combined with wings and damage buffs, and gravitation potion.