Board Thread:New on Terraria Wiki/@comment-25753700-20141124015202/@comment-26993120-20160222071739

This strategy has worked for me with most bosses, and for the ones it hasn't I've used variations. I call it... THE BOSS HOUSE!! Build a house (surprise, surprise). It must be at least seven blocks high and fourteen long. If you make it too big, it will end up hindering you instead. Place doors on both sides of the house in case you need a quick escape. Add a campfire on the roof and a heart lantern inside. Place wood platforms on the block above the door acroos the length of the house, which creates a ledge so you can stand above the door to get out of a line of fire. Dig a pit one block deep and two blocks wide, and fill with just enough honey to give you the regeneration buff from it. The combination of honey, heart lantern, and campfire makes your health regenerate incredibly fast. Inside the house, add a bed (to set your spawn point so you can continue a fight) and a chest (to place summoning items, weapons you don't want to carry everywhere, etc.). Light the boss house with torches, along with the surrounding area to lower normal enemy spawn rates. When you are ready to fight the Destroyer, go to the house, set your spawn, and grab your weapons. When the Destroyer appears, immediately jump to the side of him and start melee attacks until his entire body makes a pass. If you feel that you can do better with a magic or ranged weapon, use that instead at first. During the fight, Probes will spawn and shoot you. This is when the house comes in handy - all Probes outside of the house will have to get close to you to actually hurt you - within the range of your weapons. Inside your house, continually dip in the honey to refresh the buff, and if you feel brave, go outside and shoot the Destroyer while his body is high in the air. Other than that, stay in the house. All the red lights on the Destroyer spawn Probes - damaging the segment's will smash the lights. Using the house strategy and only a melee weapon and healing potions, I beat the Destroyer fairly easily. Just be good at dodging and you should be fine! This works better for Skeleton Prime because of all his arms, but isn't as effective against the Twins, as you will have to venture out often in their second phases. Hope this helps, good luck!