Talk:Skeletron Prime/@comment-50.45.113.67-20111213011919/@comment-4674838-20111213013931

Crystal storm + full adamantite armor (use melee helm for defense), along with not-insanely-hard-to-get accessories such as angel wings, spectre boots, obsidian shield, mana flower and sorcerer's emblem, all with the best +defense prefixes you can afford to buy, is sufficient gear to beat all of the bosses. I can 100% guarantee you that.

Strategy wise, make arena with wood platforms, run away from him and dodge his attacks and shoot him with your crystal storm. Drink your buff potions (esp. ironskin, you need as much defense as possible), gravitation (so that you can move around better) and magic power potion (so that you do more damage). When you're low on health, use health potions and any heart statues that you may happen to have (heart statues helpful and recommended but not really required). If you're on potion cooldown and you need to heal, use magic mirror to teleport to your house and immediately heal (put the nurse in your room) and return to the arena and continue the fight. This is all the guide you need. It works solo, so if you still can't do it even with the help of a friend... then I don't know, maybe get more friends, because a better guide isn't going to help you.