Board Thread:Help Desk/@comment-7860774-20130407012806/@comment-26952072-20150908044527

You're better off with a (Mythical) Magic Missile if you want to use magic against the Wall of Flesh, and if you do, then you should use a set of Jungle Armor. Alternatively, you can use the Space Gun because it can pierce The Hungry, and the Meteor armor makes it have unlimited "ammo."

But since 1.3, your best method of defeating the WoF on PC is to use the new Hellwing Bow with Hellfire Arrows and a full set of Necro Armor. That would involve semi-close combat due to the somewhat inaccurate bow, but the overall damage is worth it. For backup, take a Phoenix Blaster with whatever bullets you have.