Board Thread:General Discussion/@comment-24271732-20131216230753/@comment-1466854-20131217090149

As he said, chlorophyte bullets are easily the best for damage, aim, etc. and will home in on your enemies. If you can't afford or maintain them, party bullets are the best -cheap- bullets you can get (high knockback and damage), though some will prefer crystal bullets (usually for minibosses and bosses), cursed bullets (decent damage and DoT without the confetti mess from party bullets), or ichor bullets (built-in defense debuff).