Tipsy

Tipsy is a debuff that decreases a player's defenses while at the same time improving their effectiveness in melee. The exact effects are as follows:
 * -4 defense
 * +2% critical hit on melee attacks
 * +10% melee attack speed
 * +10% melee damage

Note that the effects of this debuff are (arguably) beneficial, but it still counts as a debuff and therefore can't be removed at will by right clicking its icon.