It seems to have a charge pattern similar to that of the Queen Bee. Players should be advised that she can charge through walls that are at least two blocks thick. As the player fights Mothron, she will lay Mothron Eggs which, after a while, will hatch into Baby Mothrons that have a similar attack pattern to the Mothron itself. However, these eggs can be killed before hatching. Therefore, Piranha Gun can be a powerful weapon against it.
- Mothron is a reference to Mothra, a giant moth that appears in several films in the Godzilla franchise.
- Rarely, while fighting Mothron, it disappears immediately without any drops. This can happen even if its health hasn't been completely depleted yet and its visible in the screen. (May only be for PC)
- Added to the game.