Potions are consumable items that either recover the user's health and/or mana either instantaneously or over time, or grant temporary buffs or debuffs to the user. Potions are commonly found in natural chests and Pots, can be dropped by enemies, purchased from NPCs, or crafted. Most potions can be crafted at a Placed Bottle or Alchemy Table, but flasks must be crafted at an Imbuing Station.
Potion buffs can be canceled at any time by right-clicking the buff icon (), by selecting the buff icon and canceling it in the equipment menu ( ), by selecting the buff with + / then canceling the buff with (), by double-tapping the buff icon (), or by canceling the buff from the buffs screen (). All potion buffs (including food buffs) are lost when dying, or when leaving and rejoining the world.
These potions restore health, mana, or even both at the same time. They are limited in use by the Potion Sickness and Mana Sickness debuffs, respectively. The Potion Sickness debuff duration can be reduced with a Charm of Myths or a Philosopher's Stone.
These grant the character a temporary, usually short-lived buff when consumed. They are crafted at a Placed Bottle or an Alchemy Table. Pressing the buff key (Quick Buff by default) will consume one of each of the player's buff potions in their inventory.
These grant the character a temporary melee and whips-specific buff when consumed. Only one flask buff can be active at a time. Crafted at an Imbuing Station.
These are potions that do not fit in the other categories.
- Certain potions' sprites use bottles that correlate with real-life flasks. These include:
- All of the Lesser potions, using an Erlenmeyer flask.
- The Strange Brew, using a Florence flask.
- The Ironskin, Regeneration, Swiftness, and Gills Potions all use test tubes.
- The in-game flasks are slight modifications of the round bottom flasks with special stoppers.
- All other potions seem to be extreme modifications of the Dewar flask or Erlenmeyer flask.
- All potions (excluding the Recovery potions) use a glass stopper.
- The sprite for the Wiesnbräu is a reference to a popular drinking glass, and has been seen in the 2006 American comedy film Beerfest.
- On , if the player quickly uses a potion right after they leave their inventory, the potion will be used, but not consumed. However, the buff/debuff from it will only last 1 minute. Note that this might not work every time.
- Some potions can only be crafted in worlds with the proper evil biome:
- Note that since 18.104.22.168 update, you can place a Dryad in graveyard biome and get opposite evil's seeds, so all of the following potions are available to craft on every world.
- Thorns and Wrath potions can only be crafted in worlds with Corruption ingredients.
- Heartreach and Rage potions can only be crafted in worlds with Crimson ingredients.
- Both the Heartreach and Thorns Potions can be found in Chests, regardless of world type. Additionally Heartreach potions can be found in Crates. However, this represents a limited (non-renewable) supply for Thorn Potions.
- Of these four potions, only the Heartreach potion can be obtained from Crates.
- Desktop 22.214.171.124: Changed buff potion durations. Added 61 food items
- Desktop 126.96.36.199: Super Healing Potions, Strange Brew, Bacon, Gender Change Potion, and Wormhole Potions added. Each potion given new sprites.