强效魔力药水是一种使用时能够恢复 200 魔力的药水，并且是位于超级魔力药水和诡药之后魔力恢复量第三的魔力恢复物品。不像大多数药水，强效魔力药水无法制作。它们能够以每个5 / 10 的价格从巫师处购买，或由生物群落宝箱怪掉落。On the 主机版、 前代主机版、和版, they can additionally be obtained from Golden Crates, but on the 电脑版和 移动版, they cannot be obtained outside of Hardmode.
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- Greater Mana Potions have a maximum stack of 75, which is the same as Mana Potions and 1.5 times the max of Lesser Mana Potions. It would cost 375 to purchase a full stack from the Wizard.
- Using the Greater Mana Potion gives the player a unit price of 2.5 / 5 per 1 mana.
- Even though the Mana Potion is used to craft the Mana Flower, the Mana Flower's sprite shows both the shape and two yellow bands of the Greater Mana Potion.
- The Greater Mana Potion is identical in name and fairly similar in appearance to Mana Potions in the action role-playing hack-and-slash computer video game Diablo 2.
- 电脑版 188.8.131.52：
- Buy/Sell price decreased from 10 / 2 to 5 / 1.
- Sprite updated.
- 电脑版 1.2.3：
- Used to craft Super Mana Potions.
- Consuming any Mana Potion will enact the Mana Sickness debuff.
- Max Stack increased from 50 to 75.
- 电脑版 1.2：
- Buy/Sell price increased from 5 / 1 to 10 / 2.
- Max stack reduced from 99 to 50.
- 电脑版 1.1：Introduced.
- Switch版 1.0.711.6：Introduced.